Results 1–3 of 3 for epimer
Epimers are diastereoisomers that have the opposite configuration at only one of two or more chiral centers present in the respective molecular entities. For example D-glucose and D-mannose, which differ only in the stereochemistry at C-2, are epimers, as are D-glucose and D-galactose (which differ at C-4).
Epimerization is an interconversion of epimers. If the conversion of one epimer to another is catalyzed by an enzyme, the enzyme is an epimerase.
Mutarotation is the change in optical rotation accompanying epimerization. In carbohydrate chemistry this term usually refers to epimerization at the hemiacetal carbon atom. In general α- and β-form are stable solids, but in solution they rapidly equilibrate. For example, D-glucose exists in an equilibrium mixture of 36 % α-D-glucopyranose and 64 % β-D-glucopyranose, with only a tiny fraction in the open-chain form. The equilibration occurs via the ring opening of the cyclic sugar at the anomeric center with the acyclic form as the intermediate. Mutarotation was discovered by French chemist Augustin-Pierre Dubrunfaut (1797-1881) in 1846.
Generalic, Eni. "Epimer." Croatian-English Chemistry Dictionary & Glossary. 29 June 2022. KTF-Split. {Date of access}. <https://glossary.periodni.com>.
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